Polypharmacy and potential drug-drug interactions among o...

연구 요약

Polypharmacy and potential drug-drug interactions among older patients: A cross-sectional baseline study pre-2023 Palestine crisis.

Science progress 학술지에 발표된 이 연구는 Mosleh R, Jarrar Y, Qadous SG 외 연구팀이 수행하였습니다.

핵심 내용

ObjectivesPolypharmacy, the concurrent use of multiple medications, presents significant challenges and risks in modern healthcare systems, particularly among older individuals and those with chronic diseases. This study aimed to investigate the prevalence and determinants of potential drug-drug interactions (pDDIs) among older adults at Jerusalem, Gaza Strip, and the West Bank of Palestine. This study serves as a baseline assessment before the October 2023 Palestine crisis, which led to extensive forced displacement.MethodsThis cross-sectional study examined the prescribed medications for 403 participants, conducted between May 2023 and August 2023, 2 months prior to the invasion of Gaza. This study served as a baseline evaluation of the potential pDDIs before the 7 October 2023 of Palestine crisis. Participants recruited using simple random sampling technique from medical records' lists of patients. They were interviewed at various pharmacies and hospitals across Jerusalem, the Gaza Strip, and the West Bank of Palestine using an online questionnaire created via Google Forms. Descriptive, Univariate and multivariate analyses, and Chi-square tests were carried-out by SPSS v21.ResultsThe study revealed a high prevalence of pDDIs among the Palestinian population, with a substantial proportion of participants experiencing moderate to major interactions. Participants receiving a higher number of medications were significantly more likely to experience major pDDIs.

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의사/약사의 전문적 판단을 대체하지 않습니다 (PMID: 41671293)