Antipsychotic prescribing patterns in a state psychiatric hospital with predomin...

연구 요약

Antipsychotic prescribing patterns in a state psychiatric hospital with predominantly forensic admissions.

Frontiers in psychiatry 학술지에 발표된 이 연구는 Vadiei N 외 연구팀이 수행하였습니다.

이 연구는 'Antipsychotic prescribing patterns in a state psychiatric hospital with predominantly forensic admissions.'에 대한 과학적 분석을 제공합니다.

핵심 내용

BACKGROUND: There are currently no published studies evaluating antipsychotic prescribing patterns in state hospital settings in the United States. This data is important to review since state hospitals involuntarily commit patients with serious mental illness (SMI) to receive treatment with antipsychotic medications, which are associated with a multitude of dose-dependent adverse effects. METHODS: This cross-sectional study describes antipsychotic prescribing patterns at a single state psychiatric hospital with predominantly forensic admissions. Data was collected via chart review at a single point in time, including demographic data and clinical characteristics such as admission type, neuropsychiatric diagnoses, length of stay, antipsychotic selection and dosing, and total number of scheduled antipsychotics. If the total daily dose of the scheduled antipsychotic was greater than the recommended typical maximum dose, it was considered 'high-dose' antipsychotic use. RESULTS: Among 212 state hospital admissions, nearly two-thirds of patients were prescribed ≥ 1 antipsychotic at either the recommended typical maximum dose (N=76; 35.8%) or above the typical maximum dose (N=62; 29.2%). Several patients were prescribed antipsychotic polypharmacy (APP) (two scheduled antipsychotics [N = 76; 35.8%]; three scheduled antipsychotics [N = 13; 6.1%]). About one-third of patients were prescribed olanzapine (N = 76; 35.8%), and about a quarter of patients were prescribed clozapine (N = 51; 24.1%) and/or paliperidone (including Invega Sustenna) (N = 49; 23.1%). One-fifth of patients were prescribed a first-generation antipsychotic (N = 43; 20.3%). Nearly one-third of patients were prescribed a long-acting injectable antipsychotic (LAIA) (N = 69; 32.5%). CONCLUSION: High-dose antipsychotic use and APP was common in this U.S. state psychiatric hospital. Larger, multicenter studies are needed to determine how antipsychotic prescribing patterns vary between U.S. state hospitals. Testing the development and implementation of antipsychotic stewardship programs in state hospital settings is recommended to establish best practices for monitoring antipsychotic use patterns and associated health outcomes.

일반인을 위한 해석

구체적인 실천 사항은 담당 의사 또는 약사와 상담하시기 바랍니다.

실천 사항

• 현재 복용 중인 약물이나 영양제에 대해 궁금한 점이 있다면 담당 의사 또는 약사와 상담하시기 바랍니다
• 약물이나 영양제의 용법·용량을 임의로 변경하지 마세요
• 이상 반응이 나타나면 즉시 전문가에게 문의하세요

의사/약사의 전문적 판단을 대체하지 않습니다 (PMID: 41694123)

📄 [전문 보기 (Markdown)](fulltext/41694123-antipsychotic-prescribing-patterns-in-a-state-psychiatric-ho.md)