Prevalence of potentially inappropriate medication prescr...

연구 요약

Prevalence of potentially inappropriate medication prescribing, inappropriate medication use, prescription omission and drug interactions among older adults in Ethiopia: a systematic review and meta-analysis.

BMJ open 학술지에 발표된 이 연구는 Yazie TS, Alemu MA, Zewdu WS 외 연구팀이 수행하였습니다.

핵심 내용

OBJECTIVE: To determine the prevalence of potentially inappropriate prescribing (PIP), potentially inappropriate medication (PIM), potential prescription omission (PPO), potentially harmful drug-drug interactions (PDDI) and identify associated factors among older Ethiopians. DESIGN: Systematic review and meta-analysis DATA SOURCE: We searched PubMed, HINARI, Scopus and Web of Science databases to identify eligible studies published up to 31 October 2025. STUDY SELECTION: Observational studies reported the prevalence of PIP, PIM, PPO and PDDI among older adults from any healthcare settings were screened. DATA EXTRACTION AND SYNTHESIS: Two independent reviewers selected studies, extracted data and assessed the risk of bias. The quality and risk of bias of the studies were assessed using the Newcastle-Ottawa scale and Hoy risk of bias tool, respectively, while the certainty of evidence of outcomes was assessed using Grading of Recommendations, Assessment, Development and Evaluation based on Cochrane recommendations. We used a random-effects model for analyses to estimate the pooled prevalence and associated factors. All data analyses were done using Stata V.17 software. MAIN OUTCOMES AND MEASURES: The national prevalence of PIP, PIM, PPO and PDDI was estimated as main outcomes. Variations were estimated based on regions, age groups, outcome evaluation tool, disease type and healthcare setting.

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의사/약사의 전문적 판단을 대체하지 않습니다 (PMID: 41775477)